1. Set the oven at 450°F to preheat, and while you wait, mix the spices in a bowl. Sprinkle the spice mix over the pork butt and rub it into the flesh.
2. Place a large iron skillet on the stove at high heat, and sear the pork butt on all sides till it browns nicely. Transfer the seared meat to a baking dish.
3. Cover the dish with foil and place it in the oven. Drop the heat to 325°F and cook for 3 hours. Afterward, take off the foil and cook for an extra hour. The roast is done at an internal temperature of 165 to 180°F. It should also be pull-apart tender.
4. Set it down and leave it to cool for some minutes. This waiting period allows the juices to redistribute. Shred and serve however you please.

Also, consider this video recipe for more ways to cook pork butt.