Preheat the oven to 400 degrees. Lightly grease a 9×13 inch baking dish. Bring a large pot of lightly salted water to a boil. Add elbow macaroni and cook according to package directions.
While the water is coming to a boil for the pasta, in a large saucepan melt the butter over medium heat. Add the flour and whisk together. Cook for 1 minute. Slowly pour in the milk, a little at a time
while whisking constantly until the milk is incorporated. Cook while whisking for about 4-5 minutes or until the mixture thickens. Remove the milk mixture from the heat and stir in the cheeses until melted.
Drain the pasta and toss it with the cheese sauce. Stir in the prosciutto and jalapeno peppers. Pour the mixture into the prepared casserole dish. Top evenly with buttered breadcrumbs.
Place into the oven and bake at 400 degrees for 20 minutes or until bubbly and the breadcrumbs are golden brown.